Michelangelo is the first major Renaissance artist credited with painting the Sistine Chapel. His work on the chapel’s ceiling, completed in 1512, is a monumental achievement in art and showcases his mastery of the human form and perspective. The frescoes depict biblical stories, including the famous "Creation of Adam," and highlight the interplay of divine and human elements. Michelangelo's innovative techniques and dramatic compositions significantly influenced the course of Western art, making the Sistine Chapel a prime example of Renaissance artistry and a reflection of the period's religious and cultural values.