The significance of the Acadians' expulsion from Canada during the French and Indian War (1754-1763) lies in its impact on cultural identity and demographics. The British forcibly removed thousands of Acadians from their ancestral lands in present-day Nova Scotia, often due to suspicions of their loyalty to France. This event, known as the Great Expulsion, led to significant suffering and displacement, with many Acadians resettling in Louisiana, where they would develop a unique cultural identity. The expulsion is remembered as a poignant example of colonial intolerance and displacement.