The main outcome of the Reformation in Europe was the significant fragmentation of the Christian Church, which led to the establishment of Protestant denominations separate from Roman Catholicism. It sparked religious, political, and cultural changes across Europe, diminishing the Catholic Church's influence and promoting the rise of individual interpretation of the Scriptures. Additionally, the Reformation encouraged nationalistic sentiments, leading to further conflicts, such as the Thirty Years' War. It also laid the foundation for the modern secular state and influenced subsequent movements for religious freedom and modern democracy.