Cortisol is commonly associated with stress in the body. As a key stress hormone, cortisol plays a role in the body's fight-or-flight response. Elevated levels can result from chronic stress, leading to various health issues such as weight gain, high blood pressure, and a weakened immune system. Managing stress through exercise, mindfulness, and other relaxation techniques can help maintain healthy cortisol levels, improving overall health and reducing the risk of stress-related complications.