The sea that separates Italy from the Balkan Peninsula is the Adriatic Sea. This body of water is situated to the east of Italy and is known for its deep blue waters, picturesque coastline, and numerous islands. The Adriatic Sea has significant historical importance, serving as a trade route for various civilizations over the centuries, including the Romans and Venetians. It supports a rich marine ecosystem and is popular for tourism, attracting visitors to its charming towns, beaches, and cultural sites along both the Italian and Balkan coasts.