Effective strategies for preparing for the interview round of UPSC include thorough knowledge of personal achievements, current affairs, and societal issues. Candidates should prepare to articulate their viewpoints on various topics clearly and confidently. Mock interviews with peers or mentors can help simulate the actual experience, providing valuable feedback. Familiarity with the interview panel's expectations and format is crucial, along with managing anxiety through relaxation techniques. Reflecting on past experiences for relatable anecdotes can also illustrate one's personality and values, adding depth to responses during the interview.