During the UPSC interview, candidates should embrace certain do's and avoid specific don’ts. Do's include being well-prepared, demonstrating confidence, and maintaining a positive attitude. It’s crucial to articulate thoughts clearly and engage thoughtfully with the panel. Conversely, aspirants should avoid overconfidence, giving vague responses, or criticizing others. Displaying humility, acknowledging limitations, and being honest about knowledge can create a positive impression during this critical evaluative stage.