Knowledge of international relations is significant in the UPSC syllabus, as it encompasses key aspects of India's foreign policy and global diplomacy. Topics like bilateral relations, global governance, and international organizations are critical for both the preliminary and mains exams. Understanding these concepts equips aspirants to analyze how global dynamics affect India's national interest. Additionally, awareness of international treaties and agreements can enhance their performance in interviews, showcasing their preparedness to engage with complex geopolitical issues.