Aspirants can handle disappointments during the UPSC preparation journey by fostering a positive mindset and focusing on personal growth. It's crucial to view setbacks as opportunities for learning rather than failures. Setting realistic goals and celebrating small achievements can boost morale. Engaging in supportive peer groups or counseling can provide emotional relief and perspective. Practicing stress management techniques such as meditation or exercise helps maintain mental well-being. Finally, seeking the guidance of mentors or experienced candidates can provide new strategies and encouragement to overcome hurdles effectively.