The Italian artist and architect who designed St. Peter's Basilica in Vatican City is Michelangelo Buonarroti. His contributions to the design and construction of the basilica during the Renaissance period reflect his exceptional talent and innovative approach to architecture. Michelangelo's work is characterized by grandeur, intricate detailing, and a profound sense of spirituality. The basilica remains a symbol of Christianity and architectural achievement, attracting millions of visitors annually to its stunning interiors and iconic dome.