The first woman to serve as the U.S. Secretary of State was Madeleine Albright. Appointed by President Bill Clinton in 1997, Albright significantly influenced U.S. foreign policy, focusing on issues like human rights and global democracy. Before becoming Secretary of State, she served as the U.S. Ambassador to the United Nations, where she advocated for international cooperation and security. Albright's groundbreaking role paved the way for future women in leadership positions within the U.S. government. Her legacy as a diplomat and advocate for global political engagement remains influential in contemporary politics.