The significant scientist known for his Pasteurization process is Louis Pasteur. His groundbreaking research in the 19th century addressed the spoilage of food and drink caused by microorganisms. Pasteur developed the pasteurization technique to heat liquids to eliminate harmful bacteria without compromising taste or quality. This innovation revolutionized food safety, leading to the widespread adoption of pasteurization in dairy products and beverages. Pasteur's contributions to microbiology also laid the foundation for advances in the fields of vaccination and germ theory.