The famous artist known for the "Mona Lisa" painting is Leonardo da Vinci. His groundbreaking work exemplifies the Renaissance art movement, showcasing innovative techniques such as sfumato and chiaroscuro. The "Mona Lisa," famous for her enigmatic smile, represents both artistic mastery and a complex understanding of human emotion. Da Vinci's legacy extends beyond painting to encompass scientific inquiry and invention, making him a quintessential figure in the history of art and science.